Clinical Disclaimer: Maximum doses include all routes of administration combined. Reduce by 50% in patients with severe cardiac disease, hepatic dysfunction, or methemoglobinemia risk (prilocaine). Adrenaline limit: 0.2 mg (4 cartridges of 1:100,000) in healthy adults; 0.04 mg in cardiovascular disease. Always verify against your local prescribing reference and apply clinical judgment.